一、中心簡(jiǎn)介

首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（簡(jiǎn)稱創(chuàng)新中心）是北京市新成立的具有獨(dú)立法人資格的新型研發(fā)機(jī)構(gòu)。創(chuàng)新中心以推動(dòng)醫(yī)學(xué)科學(xué)發(fā)展、改善人類健康為目標(biāo)，開展生物醫(yī)學(xué)研究，致力于提升醫(yī)學(xué)科學(xué)創(chuàng)新與成果轉(zhuǎn)化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學(xué)家，與首都醫(yī)學(xué)教育和科學(xué)研究?jī)?yōu)質(zhì)資源緊密合作，打造多學(xué)科交叉融合的科研平臺(tái)，綜合自由探索、醫(yī)學(xué)目標(biāo)導(dǎo)向、有組織科研等途徑，實(shí)踐新型科研模式和體制機(jī)制，逐步推進(jìn)醫(yī)教研產(chǎn)的深度融合，培養(yǎng)適應(yīng)醫(yī)學(xué)科學(xué)創(chuàng)新發(fā)展的優(yōu)秀人才。

二、實(shí)驗(yàn)室介紹

王立銘，首都醫(yī)學(xué)科學(xué)創(chuàng)新中心資深研究員，遺傳與分子醫(yī)學(xué)研究所所長(zhǎng)，博士生導(dǎo)師。

實(shí)驗(yàn)室長(zhǎng)期關(guān)注機(jī)體代謝的神經(jīng)生物學(xué)調(diào)控機(jī)理研究。在Nature、Nature Neuroscience、PNAS、e Life、Cell Research等知名期刊發(fā)表多篇研究論文。同時(shí)致力于大眾科學(xué)傳播和教育，出版專著《吃貨的生物學(xué)修養(yǎng)》《上帝的手術(shù)刀》《生命是什么》《笑到最后》《給忙碌者的病毒科學(xué)》等科普書籍，發(fā)行量超30萬(wàn)冊(cè)，先后獲得國(guó)家圖書館“文津圖書獎(jiǎng)”、科技部全國(guó)優(yōu)秀科普作品、“吳大猷科普著作獎(jiǎng)”等獎(jiǎng)勵(lì)。

掃碼了解更多_二維碼（請(qǐng)點(diǎn)擊鏈接查看詳情）

三、實(shí)驗(yàn)室研究方向

包括人類在內(nèi)，動(dòng)物的生存和健康很大程度上依賴于對(duì)機(jī)體能量和必需營(yíng)養(yǎng)物質(zhì)水平的精確調(diào)節(jié)和維持，而中樞神經(jīng)系統(tǒng)在這方面發(fā)揮了不可或缺的重要功能。通過(guò)實(shí)時(shí)的感知機(jī)體內(nèi)部的能量和營(yíng)養(yǎng)物質(zhì)儲(chǔ)備，以及環(huán)境中食物的分布，中樞神經(jīng)系統(tǒng)可以通過(guò)精密的行為調(diào)節(jié)，保證動(dòng)物機(jī)體的代謝平衡。而這一調(diào)控機(jī)制一旦被破壞，將可能引發(fā)包括進(jìn)食障礙、肥胖癥在內(nèi)的一系列神經(jīng)和代謝系統(tǒng)疾病。

實(shí)驗(yàn)室對(duì)神經(jīng)系統(tǒng)與代謝系統(tǒng)相關(guān)聯(lián)的生物學(xué)問(wèn)題有廣泛的興趣。近期的研究工作將主要利用定量行為分析、活體鈣成像、遺傳篩選和分析、單細(xì)胞轉(zhuǎn)錄組和環(huán)路追蹤等技術(shù)，在果蠅和小鼠模型中研究如下兩個(gè)相互獨(dú)立但互相關(guān)聯(lián)的生物學(xué)問(wèn)題：

l        神經(jīng)系統(tǒng)如何參與機(jī)體能量和重要營(yíng)養(yǎng)物質(zhì)代謝的調(diào)控

l        動(dòng)物各器官如何協(xié)同參與機(jī)體代謝的調(diào)控和代謝病的發(fā)生

四、崗位信息

崗位1：科研助理（若干）

01、崗位職責(zé)

1.協(xié)助團(tuán)隊(duì)或獨(dú)立開展課題研究；

2.參與實(shí)驗(yàn)室日常管理，提供公共事務(wù)支持。

02、任職要求

1.細(xì)胞生物學(xué)、神經(jīng)生物學(xué)相關(guān)專業(yè)碩士及以上學(xué)歷，有相關(guān)實(shí)驗(yàn)技術(shù)經(jīng)驗(yàn)者可放寬到本科；

2.抗壓能力強(qiáng)，熱愛(ài)科研，有志于繼續(xù)從事科研工作；

3.品行端正，動(dòng)手能力強(qiáng)，工作認(rèn)真負(fù)責(zé)，具備良好的團(tuán)隊(duì)協(xié)作能力；

4.通過(guò)CET-6或同等英語(yǔ)水平，或有攻讀研究生計(jì)劃者優(yōu)先。

03、研究方向

1.進(jìn)行細(xì)胞方面的相關(guān)科研實(shí)驗(yàn)，日常的細(xì)胞事務(wù)管理、質(zhì)粒的轉(zhuǎn)染、穩(wěn)轉(zhuǎn)細(xì)胞系的構(gòu)建、細(xì)胞染色、成像、KO文庫(kù)和代謝物篩選等；

2.進(jìn)行神經(jīng)環(huán)路方面相關(guān)科研實(shí)驗(yàn)，腦立體定位注射、光纖記錄、光/化學(xué)遺傳學(xué)、雙光子活體成像、組織透明化成像等；

3.進(jìn)行果蠅神經(jīng)環(huán)路方面相關(guān)科研實(shí)驗(yàn)，包括行為學(xué)檢測(cè)、在體及離體鈣成像、熒光腦片拍攝、光遺傳學(xué)、果蠅庫(kù)管理等。

崗位2：博士后（2名）

01、崗位職責(zé)

1.在導(dǎo)師及合作導(dǎo)師共同指導(dǎo)下參與實(shí)驗(yàn)室的課題研究；

2.協(xié)助處理實(shí)驗(yàn)室公共事務(wù)。

02、任職要求

1.獲得或即將獲得生物學(xué)/基礎(chǔ)醫(yī)學(xué)相關(guān)領(lǐng)域博士學(xué)位，畢業(yè)時(shí)間一般不超過(guò)三年；

2.以第一作者身份在領(lǐng)域內(nèi)主流期刊發(fā)表過(guò)或即將發(fā)表研究論文；

3.具備獨(dú)立開展科研工作能力，對(duì)科研有熱情和嚴(yán)謹(jǐn)認(rèn)真的態(tài)度，有團(tuán)隊(duì)合作精神；

4.對(duì)代謝和代謝相關(guān)疾病有強(qiáng)烈興趣、有細(xì)胞生物學(xué)或神經(jīng)生物學(xué)研究背景者同等條件下優(yōu)先考慮。

五、福利待遇

1.根據(jù)應(yīng)聘者的工作經(jīng)驗(yàn)和能力，提供具有市場(chǎng)競(jìng)爭(zhēng)力的薪酬（詳情面談）；

2.享受五險(xiǎn)一金、帶薪年假、體檢和補(bǔ)充醫(yī)療保險(xiǎn)等；

3.支持個(gè)人發(fā)展，提供必要的工作相關(guān)專業(yè)培訓(xùn)；

4.為有科研熱情且有一定科研能力的應(yīng)聘者提供充足的深造機(jī)會(huì)。

六、申請(qǐng)方法

應(yīng)聘者請(qǐng)將以下材料按照如下順序打包發(fā)送至igm@cimrbj.ac.cn， 各項(xiàng)材料以“姓名+資料名稱”命名，郵件主題請(qǐng)注明“應(yīng)聘者名字+具體應(yīng)聘職位”。

1.個(gè)人簡(jiǎn)歷、研究興趣或計(jì)劃；

2.學(xué)術(shù)成果或獎(jiǎng)勵(lì)清單（如有）；

3.2名推薦人的姓名及聯(lián)系方式（僅限博士后應(yīng)聘）；

4.其他能證明科研能力的相關(guān)電子文件。

聯(lián)系人：任老師

聯(lián)系地址：北京市豐臺(tái)區(qū)右安門外西頭條10號(hào)-首都醫(yī)學(xué)科學(xué)創(chuàng)新中心

本招聘長(zhǎng)期有效，至招聘到合適人選為止。

ABOUT CIMR

Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of the Capital Medical University, Beijing, China and committed to building a scientist-centered governance framework and fostering a diverse and inclusive work environment. For more information, please visit our website: www.cimrbj.ac.cn

ABOUT IGM

The Institute for Genetics and Molecular Medicine (IGM) is dedicated to advancing research on congenital genetic diseases, cancer, metabolic disorders, and immune-related diseases. We focus on integrating genetic research with the development of diagnostic and therapeutic technologies, aiming to translate disease research into clinical applications. Leveraging the abundant clinical resources of affiliated hospitals of Capital Medical University, IGM supports translational research that bridges bench to bedside. We encourage close collaboration between laboratories and clinical departments to identify disease-causing genes from clinical samples, conduct mechanistic studies and therapeutic development in the lab, and rapidly validate and optimize diagnostic and treatment approaches in patient populations.

Laboratory Introduction

Liming Wang is Investigator and Director of Institute for Genetics and Molecular Medicine, Chinese Institutes for Medical Research, Beijing, and doctoral supervisor.

The laboratory has long focused on researching the neurobiological regulatory mechanisms of body metabolism. It has published numerous research papers in renowned journals such as Nature, Nature Neuroscience, PNAS, eLife, and Cell Research. Meanwhile, it is committed to public science communication and education, publishing popular science books including The Biology Cultivation of Foodies, God's Scalpel, What Is Life, Laughing to the End, and Virus Science for the Busy, with a circulation of over 300,000 copies. The laboratory has successively won awards such as the "Wenjin Book Award" from the National Library of China, the National Excellent Popular Science Works Award from the Ministry of Science and Technology, and the "Wu Dayou Popular Science Writing Award".

Lab website:QR→（請(qǐng)點(diǎn)擊鏈接查看詳情）

Laboratory Research Directions

The survival and health of animals, including humans, largely depend on the precise regulation and maintenance of energy and essential nutrient levels in the body, and the central nervous system (CNS) plays an indispensable role in this regard. By real-time sensing of energy and nutrient reserves within the body, as well as the distribution of food in the environment, the CNS ensures metabolic balance in animals through sophisticated behavioral regulation. Once this regulatory mechanism is disrupted, it may trigger a series of neural and metabolic diseases, including eating disorders and obesity.

Our laboratory has broad interests in biological questions related to the interaction between the nervous system and metabolic system. Our recent research will primarily use techniques such as quantitative behavioral analysis, in vivo calcium imaging, genetic screening and analysis, single-cell transcriptomics, and circuit tracing in Drosophila and mouse models to investigate the following two independent but interrelated biological questions:

How does the nervous system participate in the regulation of energy and essential nutrient metabolism in the body?

How do various organs in animals collaborate in the regulation of body metabolism and the occurrence of metabolic diseases?

Open Positions

Research Assistant

Main Responsibilities

a. Assist in or independently conduct research projects.

b. Participate in laboratory management and provide administrative support.

Qualifications

a. Master’s degree or higher in cell biology, neurobiology, or related fields; bachelor’s degree holders with relevant experimental experience will also be considered on a priority basis.

b. Strong resilience, passion for research, and commitment to a scientific career.

c. High ethical standards, excellent hands-on skills, diligence, and teamwork abilities.

d. Priority given to candidates with CET-6 certificate or equivalent proof of English proficiency, or those planning to pursue graduate studies.

Research Directions

a. Engage in cell-related experiments, including cell culture management, plasmid transfection, stable cell line construction, cell staining, imaging, KO library screening, and metabolite screening.

b. Perform neurocircuitry-related experiments, such as stereotaxic brain injections, fiber photometry, optogenetics/chemogenetics, two-photon in vivo imaging, and tissue clearing imaging.

c. Engage in Drosophila neurocircuitry research, including behavioral assays, in vivo/ex vivo calcium imaging, fluorescent brain slice imaging, optogenetics, and fly stock management.

Postdoctoral Researcher

Main Responsibilities

a. Conduct independent research under the guidance of the principal investigator (PI) and co-mentors, while collaborating with team members.

b. Assist in laboratory management and public affairs.

Qualifications

a. Ph.D. degree (or expected to graduate within 6 months), generally within three years of graduation, in biology, basic medicine, or related fields.

b. First-author publication in a peer-reviewed journal (or accepted for publication).

c. Ability to conduct independent research, strong passion for science, rigorous attitude, and teamwork spirit.

d. Priority given to candidates with a strong interest in metabolism/metabolic diseases (e.g., neuro-metabolism or metabolic disorders in cancer) or backgrounds in cell biology/neurobiology.

Welfare Treatment

a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).

b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.

c. Opportunities for career development and available professional guidance.

d. Ample opportunities for further academic promotion for outstanding candidates.

How to apply

Interested applicants should compile the following materials in order and send them to igm@cimrbj.ac.cn, naming each file as "Name + Document Title" and using the email subject line "Applicant Name + Position Applied For":

a. CV and a detailed statement of research interests and future plans.

b. List of academic achievements/awards .

c. Names and contact details of two referees (for postdoctoral applicants only).

d. Additional supporting materials (e.g., representative research papers, project reports) to demonstrate research capabilities.

Contact Person: Ms. Ren

Email: igm@cimrbj.ac.cn

Address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing

This recruitment will remain open until suitable candidates are selected.

Candidates are encouraged to apply as early as possible.

信息來(lái)源于網(wǎng)絡(luò)，如有變更請(qǐng)以原發(fā)布者為準(zhǔn)。

來(lái)源鏈接：

https://mp.weixin.qq.com/s/MoFcavr9RCZ-kg7fzqxDbw

為防止簡(jiǎn)歷投遞丟失請(qǐng)抄送一份至：boshijob@126.com（郵件標(biāo)題格式：應(yīng)聘職位名稱+姓名+學(xué)歷+專業(yè)+中國(guó)博士人才網(wǎng)）