法國國家科研中心（CNRS）2022年招聘博士后（生物有機(jī)與藥物化學(xué)）
法國國家科學(xué)研究中心（法文：Centre national de la recherche scientifique），簡稱“CNRS”，成立于1939年10月19日，隸屬于法國高等教育和研究部，是法國最大的政府研究機(jī)構(gòu)，也是歐洲最大的基礎(chǔ)科學(xué)研究機(jī)構(gòu)，同時(shí)也是世界頂尖的科學(xué)研究機(jī)構(gòu)之一。它的使命是探索生命世界、物質(zhì)、宇宙和人類社會的運(yùn)作。CNRS因其在科學(xué)領(lǐng)域的卓越貢獻(xiàn)而在國際上享有盛譽(yù)，被認(rèn)為是世界科學(xué)技術(shù)發(fā)展的“風(fēng)向標(biāo)”。在2020自然指數(shù)排名中，CNRS名列世界第4。
Postdoctoral Fellow M/F In Biorganic And Medicinal Chemistry
Universities And Institutes Of France
Description
Organisation/Company: CNRS
Research Field: Biological sciences Chemistry Pharmacological sciences
Researcher Profile: Recognised Researcher (R2)
Application Deadline: 01/12/2022 23:59 - Europe/Brussels
Location: France › STRASBOURG
Type Of Contract: Temporary
Job Status: Full-time
Hours Per Week: 35
Offer Starting Date: 01/01/2023
Development of original methodologies in order to remove synthetic barriers and synthesise a library of derivatives of the lead molecules Experimental work Analyses (NMR, HPLC...), structure-activity relationships Writing of scientific reports and publications in English.
This project is part of our research programme dedicated to the optimisation of plasmodione and its superior analogue (bMD40) displaying potent antimalarial redox properties. It includes the development of methodologies allowing the introduction of groups improving the bioavailability of plasmodione, the direct functionalisation of the starting skeleton and the construction of substituted heterocyclic molecules (pyridines, oxetanes, aza- spiroalkanes...) by Suzuki-type pallado-catalysed coupling reactions. The postdoc will be in charge of experimental work, characterizations and analyses (NMR, HPLC...), writing scientific reports and will benefit from an international research environment.
The postdoctoral researcher will work in the "Bio(IN)organic and Medicinal Chemistry" team (UMR 7042 CNRS), headed by Dr Elisabeth Davioud-Charvet. This team develops projects in redox medicinal chemistry to combat several pathogenic parasites in humans. The team includes a physicochemistry research platform supported by an Engineer. In addition to 2 CNRS research directors and 1 CNRS Engineer, the group includes about 2 PhD students and 2 post- doctoral researchers. The laboratory is located at the European School of Chemistry, Polymers and Materials (ECPM) in Strasbourg (CNRS, Universities of Strasbourg and Haute-Alsace) in France. The researcher will work with the students and post-docs under the supervision of the project leader (Dr Elisabeth Davioud-Charvet, DR CNRS). His/her research work will be dedicated to the development of new lead transformations and to the elaboration of new strategies for the synthesis of heterocyclic molecules of interest in order to significantly improve their pharmacokinetic properties. The strengths of the "Bio(IN)organic and Medicinal Chemistry" team lie in the complementarity of skills at the interface of chemistry/enzymology/physicochemistry within the team, the diversity of the teams and expertise that make up the research unit Laboratoired'InnovationMoléculaire et Applications (LIMA), the international recognition of the team and of LIMA, the numerous academic and industrial collaborations, and the technological development, innovation and transfer actions. The team is also attractive for future young researchers wishing to apply for a tenure researcher position at the CNRS thanks to the multiple training opportunities it offers based on its expertise and know-how in terms of design, analysis and discovery of future drugs.
Eligibility criteria
The candidate must have a PhD in organic chemistry. He/she should have a strong background in organic synthesis and synthetic methodologies, and knowledge of medicinal chemistry. Experience in medicinal chemistry (oxetanes, heterocycles) will be an asset. We are looking for an experienced and highly motivated researcher who is committed to the project. In addition, the candidate should have good communication skills and a good team spirit
Additional comments
The application should include the following elements: - A detailed CV including at least two references, who may be contacted. - Master 2 grades, and a cover letter. - A summary of a maximum of 5 pages of past research experience.
Web site for additional job details
https: // emploi.cnrs.fr/Offres/CDD/UMR7042-ELIDAV-003/Default.aspx
Required Research Experiences
RESEARCH FIELD
Chemistry
YEARS OF RESEARCH EXPERIENCE
1 - 4
RESEARCH FIELD
Biological sciences
YEARS OF RESEARCH EXPERIENCE
1 - 4
RESEARCH FIELD
Pharmacological sciences
YEARS OF RESEARCH EXPERIENCE
1 - 4
Offer Requirements
REQUIRED EDUCATION LEVEL
Chemistry: PhD or equivalent
Biological sciences: PhD or equivalent
Pharmacological sciences: PhD or equivalent
REQUIRED LANGUAGES
FRENCH: Basic
Contact Information
Organisation/Company: CNRS
Department: Laboratoired'InnovationMoléculaire et Applications
Organisation Type: Public Research Institution
Website: https:// lima.unistra.fr
Country: France
City: STRASBOURG
為防止簡歷投遞丟失請抄送一份至：boshijob@126.com（郵件標(biāo)題格式：應(yīng)聘職位名稱+姓名+學(xué)歷+專業(yè)+中國博士人才網(wǎng)）
中國-博士人才網(wǎng)發(fā)布
聲明提示：凡本網(wǎng)注明“來源：XXX”的文/圖等稿件，本網(wǎng)轉(zhuǎn)載出于傳遞更多信息及方便產(chǎn)業(yè)探討之目的，并不意味著本站贊同其觀點(diǎn)或證實(shí)其內(nèi)容的真實(shí)性，文章內(nèi)容僅供參考。
