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美國紐約 Cellectis 公司招收博后

時間:2015-07-21來源:博士人才網(wǎng) 作者:91boshi

Postdoctoral Fellow, Immunology : New York NY10016, NY, United States

Cellectis is a gene-editing company focused on developing immunotherapies based on gene edited engineered CAR-T cells (UCART). The company’s mission is to develop a new generation of cancer therapies based on engineered T-cells.

Cellectis capitalizes on its 15 years of expertise in genome engineering – based on its flagship TALEN™ products and meganucleases and pioneering electroporation PulseAgile technology – to create a new generation of immunotherapies. CAR technologies are designed to target surface antigens expressed on cells. 
Using its life-science-focused, pioneering genome-engineering technologies, Cellectis’ goal is to create innovative products in multiple fields and with various target markets.

Cellectis is listed on the NYSE Alternext market (ticker: ALCLS) and on the Nasdaq Global Market (ticker:CLLS).

Cellectis Inc, located in New York City (Hospital District, Manhattan), invites applications for a Postdoctoral Fellow for the department of Research and Development.

This position is focused on the development of new leads for Cellectis therapeutics’ program for adoptive immunotherapy. Candidate should be highly self-motivated with the ability to excel in a fast-moving, goal-oriented environment.

Job Summary:

We are seeking a highly motivated individual with hands-on experience in immunology and tumor immunology to join us as a postdoctoral fellow. The successful candidate will work as part of the research team of Cellectis to develop next generation engineered CAR T cells for adoptive immunotherapy. Candidates must be independent to perform experiments, organize and analyze results, and communicate and present findings in team meetings.

Qualifications and Education Requirements:

• Ph.D. with a background in immunology or tumor immunology is preferred. 
• Hands-on expertise with tissue culture of cell lines and primary cells, in particular primary human T cells and/or PBMCs
• Experience in the manipulation and generation of retrovirus or lentivirus is desirable
• Direct expertise in cellular transfection/transduction methods
• Experience with multicolor flow cytometry as well as data analysis using FlowJo software 
• Experience in immunology techniques including ELISpot assays, ELISAs, colony forming unit (CFU) assay, flow-based cytokine determination, cellular proliferation and cytotoxicity assays
• Familiarity with standard molecular biology methods
• Knowledge of established genome editing technologies is desirable 
• Excellent written and communication skills in English (knowledge of French will be a plus)
• Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities

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