POSTDOCTORAL POSITION available to investigate gene expression and cellular signaling in the protozoan parasite Toxoplasma gondii. Related to the malaria parasite, Plasmodium, Toxoplasma causes birth defects and life-threatening infection in immunocompromised patients. We have shown that lysine acetylation is required for parasite growth and development, representing an exciting new drug target (Wang et al., PLoS Pathogens 2014; Jeffers & Sullivan, Eukaryotic Cell 2012; Naguleswaran et al., PLoS Pathogens 2010). Current projects involve analyzing the role of lysine acetylation in cellular signaling and gene expression, as well as the regulation of lysine acetyltransferase (KAT) enzymes.
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